Catalog:PMK050M PMK050S
Quantity: 50ul 100ul
Applications:WB, IP
Species Cross-Reactivity:H, R, M
Molecular Weight:68KD
Isotype:IgG1
Storage Buffer & Condition:
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20 °C.
Do not aliquot the antibody.
Recommended dilutions:
WB: 1:1,0 00-3,000
IHC: 1:500-1,000
Specificity:
The Lamin B1 antibody ca n detects endogenous Lamin B1 protein.
Alternative Names:
ADLD, LMB1,LMNB1 , MGC111419, OTTHUMP00000159218
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane.
The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina
matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be
involved in nuclear stability, chromatin structure and gene expression. Vertebrate la mins consist of two types, A
and B. This gene encodes one of the two B type proteins, B1.
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Application:
WB-Western blot
IHC-Immunochemistry
IF-Immunofluorescence
IP-Immunoprecipitation
ChIP-Chormatin Immunoprecipitation
Reactivity:
H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog
Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig