Known As:CD215; IL15RA; CD215 antigen; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin 15 receptor; alpha; interleukin-15 receptor subunit alpha; MGC104179
PROPERTIES
Description：Recombinant Human Interleukin-15 Receptor Subunit Alpha is produced by our
Mammalian expression system and the target gene encoding Ile31-Thr172 is
expressed with a human IgG1 Fc tag at the C-terminus.
Accession：Q13261-3
Formulation：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4
Size：10µg/50µg/500µg/1mg
Purity：> 95%
Endotoxin：< 1 EU/µg as determined by LAL test.
Predicted Mol Mass：42.2 KDa
Apparent Mol Mass：60-75 KDa, reducing conditions
Reconstitution：Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping：The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Storage：Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Background：Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and "transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15R α can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membranebound IL-15 receptor β and γ heterodimers and enables signaling to cells.
NOTE:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
