Known As:Interleukin-21; IL-21; Za11; IL21
PROPERTIES
Description:Recombinant Human Interleukin-21 is produced by our E.coli expression system and the target gene encoding Gln30-Ser162 is expressed.
Accession:Q9HBE4
Formulation:Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Size:10µg/50µg/500µg/1mg
Purity:> 95%
Endotoxin:< 0.01 EU/µg as determined by LAL test.
Predicted Mol Mass:15.6 KDa
Apparent Mol Mass:16 KDa, reducing conditions
Reconstitution:Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping:The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Storage:Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Background:IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.
NOTE:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
