Known As: Interleukin-10; Il10; IL-10; Cytokine synthesis inhibitory factor; CSIF
PROPERTIES
Description:Recombinant Mouse Interleukin-10 is produced by our E.coli expression system and the target gene encoding Ser19-Ser178 is expressed.
Accession:P18893
Formulation:Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
Size:10µg/50µg/500µg/1mg
Purity:> 95%
Endotoxin:< 0.01 EU/µg as determined by LAL test.
Predicted Mol Mass:18.9 KDa
Apparent Mol Mass:16 KDa, reducing conditions
Reconstitution:Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping:The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Storage:Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Background:Mouse Il10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL- 19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. Many viruses encode viral members of the IL- 10 family, such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV).Its main function is inhibiting the synthesis of a number of cytokines, including IFNgamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. Although human and mouse IL-10 are 81% identical at the nucleotide and amino acid level, mouse IL-10 is species-specific and does not act on human cells. lnterestingly, Human IL-10 is active on mouse cells.
NOTE:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.