重组蛋白

Recombinant Mouse Leptin

货号:PMK2200
规格:10µg/50µg/500µg/1mg
价格:110元/330元/1240元/1870元
库存:99
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Known As:Leptin; Obese Protein; Obesity Factor; LEP; OB; OBS

PROPERTIES


Description:Recombinant Mouse Leptin is produced by our E.coli expression system and the

target gene encoding Val22-Cys167 is expressed.

Accession:Q544U0

Formulation:Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, pH7.5.

Size:10µg/50µg/500µg/1mg

Purity:> 95%

Endotoxin:< 1 EU/µg as determined by LAL test.

Predicted Mol Mass:16.1 KDa

Apparent Mol Mass:14 KDa, reducing conditions

Reconstitution:Always centrifuge tubes before opening.Do not mix by vortex or pipetting.

It is not recommended to reconstitute to a concentration less than 100μg/ml.

Dissolve the lyophilized protein in distilled water.

Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping:The product is shipped at ambient temperature.

Upon receipt, store it immediately at the temperature listed below.

Storage:Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.

Reconstituted protein solution can be stored at 2-8°C for 2-7 days.

Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Background:Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body tempera-ture than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence.

NOTE:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.


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