Known As:Tumor necrosis factor ligand superfamily member 11;Tnfsf11;Osteoclast differentiation factor;ODF;Osteoprotegerin ligand;OPGL;Receptor activator of nuclear factor kappa-B ligand;RANKL;TNF-related activation-induced cytokine;TRANCE;CD254
PROPERTIES
Description：Recombinant Mouse Tumor necrosis factor ligand superfamily member 11 is
produced by our Mammalian expression system and the target gene encoding
Lys158-Asp316 is expressed with a 6His,Flag tag at the N-terminus.
Accession：O35235-1
Formulation：Supplied as a 0.2 μm filtered solution of 20mM His-HCl,100mM NaCl,10%
Trehalose,0.05% Tween80, pH5.5
Size：10µg/50µg/500µg/1mg
Purity：> 95%
Endotoxin：< 0.01 EU/µg as determined by LAL test.
Predicted Mol Mass：23 KDa
Apparent Mol Mass：23-29 KDa, reducing conditions.
Shipping：The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
Storage：Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Background：Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of mali-gnancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.
NOTE:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
