Known As: Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1
PROPERTIES
Description：Recombinant Rat Macrophage Colony-stimulating Factor 1 is produced by our
Mammalian expression system and the target gene encoding Glu33-Arg254 is
expressed.
Accession：Q8JZQ0
Formulation：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Size：10µg/50µg/500µg/1mg
Purity：> 95%
Endotoxin：< 1EU/µg as determined by LAL test.
Predicted Mol Mass：25.2 KDa
Apparent Mol Mass：46 KDa, reducing conditions
Reconstitution：Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping：The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Storage：Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Background：Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoie-tic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory process-es. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
NOTE:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
